BDBM50350576 CHEMBL1812903

SMILES: CC(C)Cn1c(CN)c(-c2ccccc2)c2ccc(cc2c1=O)C(N)=O

InChI Key: InChIKey=RTMBBRZWYRXCJT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50350576 (CHEMBL1812903) Show SMILES CC(C)Cn1c(CN)c(-c2ccccc2)c2ccc(cc2c1=O)C(N)=O Show InChI InChI=1S/C21H23N3O2/c1-13(2)12-24-18(11-22)19(14-6-4-3-5-7-14)16-9-8-15(20(23)25)10-17(16)21(24)26/h3-10,13H,11-12,22H2,1-2H3,(H2,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human DPP4 isolated from from human CaCo2 cells incubated for 15 mins using Gly-Pro-pNA.Tos substrate				Bioorg Med Chem 19: 4953-70 (2011) Article DOI: 10.1016/j.bmc.2011.06.059 BindingDB Entry DOI: 10.7270/Q2C53MVJ
					More data for this Ligand-Target Pair