BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM50350760 CHEMBL1818436

SMILES: OC[C@@H]1NCC[C@@H](O)[C@H]1O

InChI Key: InChIKey=YZNNBIPIQWYLDM-JKUQZMGJSA-N

Data: 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50350760
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lactase-glycosylceramidase (Rattus norvegicus)	BDBM50350760 (CHEMBL1818436) Show SMILES OC[C@@H]1NCC[C@@H](O)[C@H]1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometry				Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat))	BDBM50350760 (CHEMBL1818436) Show SMILES OC[C@@H]1NCC[C@@H](O)[C@H]1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometry				Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-glucosidase (Homo sapiens (Human))	BDBM50350760 (CHEMBL1818436) Show SMILES OC[C@@H]1NCC[C@@H](O)[C@H]1O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysis				ACS Med Chem Lett 2: 519-522 (2011) Article DOI: 10.1021/ml200050s BindingDB Entry DOI: 10.7270/Q28916V8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-L-fucosidase 1 (Bos taurus)	BDBM50350760 (CHEMBL1818436) Show SMILES OC[C@@H]1NCC[C@@H](O)[C@H]1O \|r\| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of bovine epididymis alpha-L-fucosidase assessed as production of p-nitrophenol by spectrophotometry				Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
Ceramide glucosyltransferase (Mus musculus)	BDBM50350760 (CHEMBL1818436) Show SMILES OC[C@@H]1NCC[C@@H](O)[C@H]1O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...				ACS Med Chem Lett 2: 519-522 (2011) Article DOI: 10.1021/ml200050s BindingDB Entry DOI: 10.7270/Q28916V8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
β-galactosidase (Bos taurus (Bovine))	BDBM50350760 (CHEMBL1818436) Show SMILES OC[C@@H]1NCC[C@@H](O)[C@H]1O \|r\| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometry				Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair