BDBM50350814 CHEMBL1819142

SMILES: Cc1[nH]c2ccccc2c1CCN(CCC(F)F)Cc1ccc(\C=C\C(=O)NO)cc1

InChI Key: InChIKey=NILBGKYIZSUBNV-ZHACJKMWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50350814 (CHEMBL1819142) Show SMILES Cc1[nH]c2ccccc2c1CCN(CCC(F)F)Cc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C24H27F2N3O2/c1-17-20(21-4-2-3-5-22(21)27-17)12-14-29(15-13-23(25)26)16-19-8-6-18(7-9-19)10-11-24(30)28-31/h2-11,23,27,31H,12-16H2,1H3,(H,28,30)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of HDAC1				J Med Chem 54: 4752-72 (2011) Article DOI: 10.1021/jm200388e BindingDB Entry DOI: 10.7270/Q23N24DW
					More data for this Ligand-Target Pair