BDBM50350837 CHEMBL1819143

SMILES: ONC(=O)\C=C\c1ccc(CN(CCc2c[nH]c3ccccc23)CCC(F)(F)F)cc1

InChI Key: InChIKey=WWESBPAOEMHYSU-MDZDMXLPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50350837 (CHEMBL1819143) Show SMILES ONC(=O)\C=C\c1ccc(CN(CCc2c[nH]c3ccccc23)CCC(F)(F)F)cc1 Show InChI InChI=1S/C23H24F3N3O2/c24-23(25,26)12-14-29(13-11-19-15-27-21-4-2-1-3-20(19)21)16-18-7-5-17(6-8-18)9-10-22(30)28-31/h1-10,15,27,31H,11-14,16H2,(H,28,30)/b10-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of HDAC1				J Med Chem 54: 4752-72 (2011) Article DOI: 10.1021/jm200388e BindingDB Entry DOI: 10.7270/Q23N24DW
					More data for this Ligand-Target Pair