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BDBM50351050 CHEMBL1819464

SMILES: COc1ccccc1N1CCN(CCn2c(=O)[nH]c3[nH]c(cc3c2=O)-c2ccc(Oc3ccccc3)cc2)CC1

InChI Key: InChIKey=FWMFZQATXSJORR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351050   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50351050
PNG
(CHEMBL1819464)
Show SMILES COc1ccccc1N1CCN(CCn2c(=O)[nH]c3[nH]c(cc3c2=O)-c2ccc(Oc3ccccc3)cc2)CC1
Show InChI InChI=1S/C31H31N5O4/c1-39-28-10-6-5-9-27(28)35-18-15-34(16-19-35)17-20-36-30(37)25-21-26(32-29(25)33-31(36)38)22-11-13-24(14-12-22)40-23-7-3-2-4-8-23/h2-14,21,32H,15-20H2,1H3,(H,33,38)
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PC sid
UniChem

Similars
Article
PubMed
 17.1n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5HT1A in CRL:CD(SD)BR-COBS rat brain hippocampus after 30 mins by liquid scintillation spectrometry

Bioorg Med Chem 19: 5260-76 (2011)


Article DOI: 10.1016/j.bmc.2011.06.043
BindingDB Entry DOI: 10.7270/Q2D50NBD
More data for this
Ligand-Target Pair