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BDBM50351060 CHEMBL1819474

SMILES: COc1ccc(cc1)-c1cc2c([nH]1)n(Cc1ccccc1OC)c(=O)n(CCN1CCN(CC1)c1ccccc1OC)c2=O

InChI Key: InChIKey=MIKBWIRMIJDSRD-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351060   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50351060
PNG
(CHEMBL1819474)
Show SMILES COc1ccc(cc1)-c1cc2c([nH]1)n(Cc1ccccc1OC)c(=O)n(CCN1CCN(CC1)c1ccccc1OC)c2=O
Show InChI InChI=1S/C34H37N5O5/c1-42-26-14-12-24(13-15-26)28-22-27-32(35-28)39(23-25-8-4-6-10-30(25)43-2)34(41)38(33(27)40)21-18-36-16-19-37(20-17-36)29-9-5-7-11-31(29)44-3/h4-15,22,35H,16-21,23H2,1-3H3
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KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 184n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5HT1A in CRL:CD(SD)BR-COBS rat brain hippocampus after 30 mins by liquid scintillation spectrometry

Bioorg Med Chem 19: 5260-76 (2011)


Article DOI: 10.1016/j.bmc.2011.06.043
BindingDB Entry DOI: 10.7270/Q2D50NBD
More data for this
Ligand-Target Pair