BDBM50351777 CHEMBL1823755

SMILES: OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)Cc1ccc(Cl)cc1

InChI Key: InChIKey=OMYGRKDVWQTYOK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50351777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1C (Homo sapiens (Human))	BDBM50351777 (CHEMBL1823755) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C28H23ClFNO4/c29-23-10-6-18(7-11-23)15-27(32)31-26(28(33)34)14-19-5-8-21-16-24(12-9-20(21)13-19)35-17-22-3-1-2-4-25(22)30/h1-13,16,26H,14-15,17H2,(H,31,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	8.0	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of human recombinant SHP1 in Tris buffer at pH 8 using OMPF as substrate				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM50351777 (CHEMBL1823755) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C28H23ClFNO4/c29-23-10-6-18(7-11-23)15-27(32)31-26(28(33)34)14-19-5-8-21-16-24(12-9-20(21)13-19)35-17-22-3-1-2-4-25(22)30/h1-13,16,26H,14-15,17H2,(H,31,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of human recombinant CDC25B				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50351777 (CHEMBL1823755) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C28H23ClFNO4/c29-23-10-6-18(7-11-23)15-27(32)31-26(28(33)34)14-19-5-8-21-16-24(12-9-20(21)13-19)35-17-22-3-1-2-4-25(22)30/h1-13,16,26H,14-15,17H2,(H,31,32)(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of TCPTP				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50351777 (CHEMBL1823755) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C28H23ClFNO4/c29-23-10-6-18(7-11-23)15-27(32)31-26(28(33)34)14-19-5-8-21-16-24(12-9-20(21)13-19)35-17-22-3-1-2-4-25(22)30/h1-13,16,26H,14-15,17H2,(H,31,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of PTP1B using p-nitrophenyl phosphate as substrate				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair