BDBM50351792 CHEMBL1823749

SMILES: OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)c1ccccc1

InChI Key: InChIKey=MDVFUMJBIBNOQG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50351792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50351792 (CHEMBL1823749) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)c1ccccc1 Show InChI InChI=1S/C27H22FNO4/c28-24-9-5-4-8-22(24)17-33-23-13-12-20-14-18(10-11-21(20)16-23)15-25(27(31)32)29-26(30)19-6-2-1-3-7-19/h1-14,16,25H,15,17H2,(H,29,30)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of PTP1B using p-nitrophenyl phosphate as substrate				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM50351792 (CHEMBL1823749) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)c1ccccc1 Show InChI InChI=1S/C27H22FNO4/c28-24-9-5-4-8-22(24)17-33-23-13-12-20-14-18(10-11-21(20)16-23)15-25(27(31)32)29-26(30)19-6-2-1-3-7-19/h1-14,16,25H,15,17H2,(H,29,30)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of human recombinant CDC25B				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50351792 (CHEMBL1823749) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)c1ccccc1 Show InChI InChI=1S/C27H22FNO4/c28-24-9-5-4-8-22(24)17-33-23-13-12-20-14-18(10-11-21(20)16-23)15-25(27(31)32)29-26(30)19-6-2-1-3-7-19/h1-14,16,25H,15,17H2,(H,29,30)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of TCPTP				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair