BDBM50352361 CHEMBL558260

SMILES: CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NCC1CC1

InChI Key: InChIKey=COTQUFSBYWGOIV-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352361 (CHEMBL558260) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NCC1CC1 Show InChI InChI=1S/C23H30N2O2S/c1-18-3-2-15-25(18)16-14-19-6-8-21(9-7-19)22-10-12-23(13-11-22)28(26,27)24-17-20-4-5-20/h6-13,18,20,24H,2-5,14-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50352361 (CHEMBL558260) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NCC1CC1 Show InChI InChI=1S/C23H30N2O2S/c1-18-3-2-15-25(18)16-14-19-6-8-21(9-7-19)22-10-12-23(13-11-22)28(26,27)24-17-20-4-5-20/h6-13,18,20,24H,2-5,14-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bioprojet-Biotech Curated by ChEMBL					Assay Description Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assay				Bioorg Med Chem Lett 21: 5378-83 (2011) Article DOI: 10.1016/j.bmcl.2011.07.006 BindingDB Entry DOI: 10.7270/Q2VX0GXK
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50352361 (CHEMBL558260) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NCC1CC1 Show InChI InChI=1S/C23H30N2O2S/c1-18-3-2-15-25(18)16-14-19-6-8-21(9-7-19)22-10-12-23(13-11-22)28(26,27)24-17-20-4-5-20/h6-13,18,20,24H,2-5,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bioprojet-Biotech Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assay				Bioorg Med Chem Lett 21: 5378-83 (2011) Article DOI: 10.1016/j.bmcl.2011.07.006 BindingDB Entry DOI: 10.7270/Q2VX0GXK
					More data for this Ligand-Target Pair