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SMILES: Nc1ncc(cc1OCc1c(Cl)cccc1Cl)-c1ccc(OCCN2CCOCC2)cc1

InChI Key: InChIKey=SWSODYAMDICARQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352563   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50352563
PNG
(CHEMBL1825140)
Show SMILES Nc1ncc(cc1OCc1c(Cl)cccc1Cl)-c1ccc(OCCN2CCOCC2)cc1
Show InChI InChI=1S/C24H25Cl2N3O3/c25-21-2-1-3-22(26)20(21)16-32-23-14-18(15-28-24(23)27)17-4-6-19(7-5-17)31-13-10-29-8-11-30-12-9-29/h1-7,14-15H,8-13,16H2,(H2,27,28)
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Article
PubMed
 2.45E+3n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assay

J Med Chem 54: 6342-63 (2011)


Article DOI: 10.1021/jm2007613
BindingDB Entry DOI: 10.7270/Q2Q52Q09
More data for this
Ligand-Target Pair