BDBM50352889 CHEMBL1824618

SMILES: Cc1ccccc1Oc1c(C(=O)N2CCNCC2)c2cccnc2n1-c1ccccc1

InChI Key: InChIKey=GPEHOBIPHPZDPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50352889 (CHEMBL1824618) Show SMILES Cc1ccccc1Oc1c(C(=O)N2CCNCC2)c2cccnc2n1-c1ccccc1 Show InChI InChI=1S/C25H24N4O2/c1-18-8-5-6-12-21(18)31-25-22(24(30)28-16-14-26-15-17-28)20-11-7-13-27-23(20)29(25)19-9-3-2-4-10-19/h2-13,26H,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant human renin using Dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate after 2 hrs by spectrofluorom...				Bioorg Med Chem Lett 21: 5487-92 (2011) Article DOI: 10.1016/j.bmcl.2011.06.112 BindingDB Entry DOI: 10.7270/Q2RX9CFJ
					More data for this Ligand-Target Pair