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BDBM50353095 CHEMBL1829130

SMILES: CCc1ccc(cc1)C(=O)Nc1cc(ccc1OCCCN1CCN(Cc2ccc(OC)c(OC)c2OC)CC1)C(=O)NC(N)=N

InChI Key: InChIKey=PEDLWHVYCCZYHA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353095   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/hydrogen exchanger 1


(Rattus norvegicus)		BDBM50353095
PNG
(CHEMBL1829130)
Show SMILES CCc1ccc(cc1)C(=O)Nc1cc(ccc1OCCCN1CCN(Cc2ccc(OC)c(OC)c2OC)CC1)C(=O)NC(N)=N
Show InChI InChI=1S/C34H44N6O6/c1-5-23-7-9-24(10-8-23)32(41)37-27-21-25(33(42)38-34(35)36)11-13-28(27)46-20-6-15-39-16-18-40(19-17-39)22-26-12-14-29(43-2)31(45-4)30(26)44-3/h7-14,21H,5-6,15-20,22H2,1-4H3,(H,37,41)(H4,35,36,38,42)
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Similars
Article
PubMed
n/an/a 49.3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysis

Eur J Med Chem 46: 4107-16 (2011)


Article DOI: 10.1016/j.ejmech.2011.06.011
BindingDB Entry DOI: 10.7270/Q27081T0
More data for this
Ligand-Target Pair