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BDBM50353146 CHEMBL1829318

SMILES: CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NC(=O)CN1C(=O)COc2ccc(F)cc12

InChI Key: InChIKey=SJSFQILVEIYOOO-KOMQPUFPSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353146   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))		BDBM50353146
PNG
(CHEMBL1829318)
Show SMILES CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NC(=O)CN1C(=O)COc2ccc(F)cc12 |r,wU:11.14,wD:8.7,(33.95,-41.42,;32.61,-40.65,;32.62,-39.11,;31.28,-41.41,;30.5,-42.74,;32.04,-42.74,;29.95,-40.64,;28.61,-41.41,;27.28,-40.64,;27.28,-39.09,;25.95,-38.32,;24.62,-39.09,;24.62,-40.63,;25.94,-41.4,;23.28,-38.32,;21.95,-39.1,;21.95,-40.64,;20.62,-38.33,;19.28,-39.1,;19.28,-40.64,;20.61,-41.41,;17.95,-41.41,;16.62,-40.64,;16.62,-39.11,;15.28,-38.34,;15.28,-36.8,;16.61,-36.03,;16.6,-34.49,;17.94,-36.79,;17.95,-38.34,)|
Show InChI InChI=1S/C20H28FN3O5S/c1-13(2)30(27,28)22-10-14-3-6-16(7-4-14)23-19(25)11-24-17-9-15(21)5-8-18(17)29-12-20(24)26/h5,8-9,13-14,16,22H,3-4,6-7,10-12H2,1-2H3,(H,23,25)/t14-,16-
KEGG

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Similars
Article
PubMed
 97n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human NPY5 receptor expressed in thymidine kinase deficient mouse LM cells after 120 mins by scintillation counting

Bioorg Med Chem Lett 21: 5573-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.078
BindingDB Entry DOI: 10.7270/Q2TQ61X3
More data for this
Ligand-Target Pair