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BDBM50353156 CHEMBL1829328

SMILES: CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NCCN1CCOc2cc(F)c(F)cc12

InChI Key: InChIKey=LQJDCNJOZWJUNO-WKILWMFISA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353156   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))		BDBM50353156
PNG
(CHEMBL1829328)
Show SMILES CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NCCN1CCOc2cc(F)c(F)cc12 |r,wU:8.7,wD:11.14,(32.07,-34.92,;30.74,-34.14,;30.74,-32.6,;29.4,-34.91,;28.62,-36.23,;30.16,-36.23,;28.08,-34.13,;26.74,-34.9,;25.41,-34.13,;24.07,-34.89,;22.74,-34.12,;22.75,-32.59,;24.07,-31.81,;25.41,-32.59,;21.41,-31.82,;20.08,-32.59,;18.74,-31.83,;17.42,-32.59,;17.42,-34.13,;16.08,-34.91,;14.75,-34.13,;14.75,-32.6,;13.41,-31.84,;13.42,-30.29,;12.08,-29.52,;14.74,-29.52,;14.74,-27.98,;16.08,-30.29,;16.09,-31.84,)|
Show InChI InChI=1S/C20H31F2N3O3S/c1-14(2)29(26,27)24-13-15-3-5-16(6-4-15)23-7-8-25-9-10-28-20-12-18(22)17(21)11-19(20)25/h11-12,14-16,23-24H,3-10,13H2,1-2H3/t15-,16-
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Article
PubMed
 110n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human NPY5 receptor expressed in thymidine kinase deficient mouse LM cells after 120 mins by scintillation counting

Bioorg Med Chem Lett 21: 5573-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.078
BindingDB Entry DOI: 10.7270/Q2TQ61X3
More data for this
Ligand-Target Pair