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BDBM50353161 CHEMBL1829333

SMILES: CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NCCN1CCSc2cc(Cl)ccc12

InChI Key: InChIKey=UWXRLNVKNZEBFP-SAABIXHNSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353161   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))		BDBM50353161
PNG
(CHEMBL1829333)
Show SMILES CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NCCN1CCSc2cc(Cl)ccc12 |r,wU:8.7,wD:11.14,(10.64,-8.81,;9.31,-8.04,;9.32,-6.5,;7.98,-8.8,;7.19,-10.13,;8.73,-10.13,;6.64,-8.03,;5.31,-8.8,;3.98,-8.02,;2.64,-8.79,;1.31,-8.02,;1.32,-6.48,;2.64,-5.7,;3.98,-6.48,;-.02,-5.71,;-1.35,-6.48,;-2.69,-5.72,;-4.02,-6.49,;-4.02,-8.03,;-5.35,-8.8,;-6.68,-8.03,;-6.68,-6.5,;-8.02,-5.73,;-8.02,-4.18,;-9.36,-3.41,;-6.69,-3.41,;-5.36,-4.18,;-5.35,-5.73,)|
Show InChI InChI=1S/C20H32ClN3O2S2/c1-15(2)28(25,26)23-14-16-3-6-18(7-4-16)22-9-10-24-11-12-27-20-13-17(21)5-8-19(20)24/h5,8,13,15-16,18,22-23H,3-4,6-7,9-12,14H2,1-2H3/t16-,18-
KEGG

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Similars
Article
PubMed
 370n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human NPY5 receptor expressed in thymidine kinase deficient mouse LM cells after 120 mins by scintillation counting

Bioorg Med Chem Lett 21: 5573-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.078
BindingDB Entry DOI: 10.7270/Q2TQ61X3
More data for this
Ligand-Target Pair