BDBM50353551 CHEMBL1830950

SMILES: CCOC(=O)c1ccc(CN2CC(C)(C)C(Oc3ccc(C#N)c(c3)C(F)(F)F)C2=O)o1

InChI Key: InChIKey=JVUKWXNRDHUQML-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50353551 (CHEMBL1830950) Show SMILES CCOC(=O)c1ccc(CN2CC(C)(C)C(Oc3ccc(C#N)c(c3)C(F)(F)F)C2=O)o1 Show InChI InChI=1S/C22H21F3N2O5/c1-4-30-20(29)17-8-7-15(31-17)11-27-12-21(2,3)18(19(27)28)32-14-6-5-13(10-26)16(9-14)22(23,24)25/h5-9,18H,4,11-12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human androgen receptor				Bioorg Med Chem Lett 21: 5230-3 (2011) Article DOI: 10.1016/j.bmcl.2011.07.048 BindingDB Entry DOI: 10.7270/Q21836WZ
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50353551 (CHEMBL1830950) Show SMILES CCOC(=O)c1ccc(CN2CC(C)(C)C(Oc3ccc(C#N)c(c3)C(F)(F)F)C2=O)o1 Show InChI InChI=1S/C22H21F3N2O5/c1-4-30-20(29)17-8-7-15(31-17)11-27-12-21(2,3)18(19(27)28)32-14-6-5-13(10-26)16(9-14)22(23,24)25/h5-9,18H,4,11-12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor by cell based assay				Bioorg Med Chem Lett 21: 5230-3 (2011) Article DOI: 10.1016/j.bmcl.2011.07.048 BindingDB Entry DOI: 10.7270/Q21836WZ
					More data for this Ligand-Target Pair