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SMILES: CN(C)C(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1

InChI Key: InChIKey=RMMKCNRVMPRUQW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353576   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 26A1


(Homo sapiens (Human))		BDBM50353576
PNG
(CHEMBL1831090)
Show SMILES CN(C)C(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1
Show InChI InChI=1S/C26H28N4O/c1-26(2,25(31)29(3)4)24(30-16-15-27-18-30)20-10-12-22(13-11-20)28-23-14-9-19-7-5-6-8-21(19)17-23/h5-18,24,28H,1-4H3
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Cardiff University

Curated by ChEMBL


Assay Description
Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation counting

J Med Chem 54: 6803-11 (2011)


Article DOI: 10.1021/jm200695m
BindingDB Entry DOI: 10.7270/Q2WM1DSJ
More data for this
Ligand-Target Pair