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SMILES: CCC(NC(=O)c1ccc(C)cc1)c1nc2ccsc2c(=O)n1Cc1ccccc1

InChI Key: InChIKey=IOAZBLSDOVWYTI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353817   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50353817
PNG
(CHEMBL1829442)
Show SMILES CCC(NC(=O)c1ccc(C)cc1)c1nc2ccsc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C24H23N3O2S/c1-3-19(26-23(28)18-11-9-16(2)10-12-18)22-25-20-13-14-30-21(20)24(29)27(22)15-17-7-5-4-6-8-17/h4-14,19H,3,15H2,1-2H3,(H,26,28)
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PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assay

J Med Chem 54: 6734-50 (2011)


Article DOI: 10.1021/jm200629m
BindingDB Entry DOI: 10.7270/Q2ZC838Z
More data for this
Ligand-Target Pair