BDBM50353987 CHEMBL1829274

SMILES: Clc1ccc(cc1)S(=O)(=O)NC(=O)Cc1cccc(Br)c1

InChI Key: InChIKey=FQYOEBSXPQCDHZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50353987 (CHEMBL1829274) Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrClNO3S/c15-11-3-1-2-10(8-11)9-14(18)17-21(19,20)13-6-4-12(16)5-7-13/h1-8H,9H2,(H,17,18)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of human recombinant (His)6-tagged HER-2 autophosphorylation pre-incubated for 10 mins by DELFIA/Time-resolved fluorometry				Bioorg Med Chem 19: 6069-76 (2011) Article DOI: 10.1016/j.bmc.2011.08.038 BindingDB Entry DOI: 10.7270/Q2DF6RM8
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50353987 (CHEMBL1829274) Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrClNO3S/c15-11-3-1-2-10(8-11)9-14(18)17-21(19,20)13-6-4-12(16)5-7-13/h1-8H,9H2,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of human recombinant (His)6-tagged EGFR autophosphorylation pre-incubated for 10 mins by DELFIA/Time-resolved fluorometry				Bioorg Med Chem 19: 6069-76 (2011) Article DOI: 10.1016/j.bmc.2011.08.038 BindingDB Entry DOI: 10.7270/Q2DF6RM8
					More data for this Ligand-Target Pair