BDBM50353996 CHEMBL1829280

SMILES: [O-][N+](=O)c1ccc(CSc2nnc(-c3ccc4OCCOc4c3)n2-c2ccccc2)cc1

InChI Key: InChIKey=MRXIRFKPPFXLDG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50353996 (CHEMBL1829280) Show SMILES [O-][N+](=O)c1ccc(CSc2nnc(-c3ccc4OCCOc4c3)n2-c2ccccc2)cc1 Show InChI InChI=1S/C23H18N4O4S/c28-27(29)19-9-6-16(7-10-19)15-32-23-25-24-22(26(23)18-4-2-1-3-5-18)17-8-11-20-21(14-17)31-13-12-30-20/h1-11,14H,12-13,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of MetAP2 after 4 hrs				Bioorg Med Chem 19: 5948-54 (2011) Article DOI: 10.1016/j.bmc.2011.08.063 BindingDB Entry DOI: 10.7270/Q28P60XC
					More data for this Ligand-Target Pair