BDBM50354063 CHEMBL1836332

SMILES: CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCOc3ccccc-23)s1

InChI Key: InChIKey=FIXIEKBXGIPZOK-HDJSIYSDSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50354063 (CHEMBL1836332) Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCOc3ccccc-23)s1 |r,wU:6.5,wD:9.12,(55.11,-10.15,;53.77,-10.92,;53,-12.26,;54.54,-12.26,;52.43,-10.14,;51.09,-10.91,;49.75,-10.14,;48.42,-10.91,;47.08,-10.13,;47.07,-8.59,;48.42,-7.82,;49.76,-8.6,;45.74,-7.8,;44.39,-8.55,;43.03,-7.93,;42.02,-9.03,;42.76,-10.34,;42.14,-11.82,;40.63,-12.21,;39.41,-11.27,;39.38,-9.67,;37.99,-9.15,;37.74,-7.69,;38.89,-6.73,;40.29,-7.25,;40.53,-8.72,;44.23,-10.04,)| Show InChI InChI=1S/C19H25N3O3S2/c1-27(23,24)20-12-13-6-8-14(9-7-13)21-19-22-18-15-4-2-3-5-16(15)25-11-10-17(18)26-19/h2-5,13-14,20H,6-12H2,1H3,(H,21,22)/t13-,14-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 21: 5436-41 (2011) Article DOI: 10.1016/j.bmcl.2011.06.124 BindingDB Entry DOI: 10.7270/Q2RN387K
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50354063 (CHEMBL1836332) Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCOc3ccccc-23)s1 |r,wU:6.5,wD:9.12,(55.11,-10.15,;53.77,-10.92,;53,-12.26,;54.54,-12.26,;52.43,-10.14,;51.09,-10.91,;49.75,-10.14,;48.42,-10.91,;47.08,-10.13,;47.07,-8.59,;48.42,-7.82,;49.76,-8.6,;45.74,-7.8,;44.39,-8.55,;43.03,-7.93,;42.02,-9.03,;42.76,-10.34,;42.14,-11.82,;40.63,-12.21,;39.41,-11.27,;39.38,-9.67,;37.99,-9.15,;37.74,-7.69,;38.89,-6.73,;40.29,-7.25,;40.53,-8.72,;44.23,-10.04,)| Show InChI InChI=1S/C19H25N3O3S2/c1-27(23,24)20-12-13-6-8-14(9-7-13)21-19-22-18-15-4-2-3-5-16(15)25-11-10-17(18)26-19/h2-5,13-14,20H,6-12H2,1H3,(H,21,22)/t13-,14-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 21: 5436-41 (2011) Article DOI: 10.1016/j.bmcl.2011.06.124 BindingDB Entry DOI: 10.7270/Q2RN387K
					More data for this Ligand-Target Pair