BDBM50354747 CHEMBL1834331

SMILES: Nc1ccc(CCNc2c(F)c(N)c3c(c2F)n(cc(C(O)=O)c3=O)C2CC2)cc1

InChI Key: InChIKey=DNBUELKLGZXIMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50354747 (CHEMBL1834331) Show SMILES Nc1ccc(CCNc2c(F)c(N)c3c(c2F)n(cc(C(O)=O)c3=O)C2CC2)cc1 Show InChI InChI=1S/C21H20F2N4O3/c22-15-17(25)14-19(27(12-5-6-12)9-13(20(14)28)21(29)30)16(23)18(15)26-8-7-10-1-3-11(24)4-2-10/h1-4,9,12,26H,5-8,24-25H2,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assay				Bioorg Med Chem Lett 21: 5948-51 (2011) Article DOI: 10.1016/j.bmcl.2011.07.073 BindingDB Entry DOI: 10.7270/Q23T9HMH
					More data for this Ligand-Target Pair