BDBM50354781 CHEMBL1834462

SMILES: ONC(=O)c1cnc(Nc2nnc(o2)-c2ccccc2)nc1

InChI Key: InChIKey=VOBVGNWCGGVORB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50354781 (CHEMBL1834462) Show SMILES ONC(=O)c1cnc(Nc2nnc(o2)-c2ccccc2)nc1 Show InChI InChI=1S/C13H10N6O3/c20-10(19-21)9-6-14-12(15-7-9)16-13-18-17-11(22-13)8-4-2-1-3-5-8/h1-7,21H,(H,19,20)(H,14,15,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas University Curated by ChEMBL					Assay Description Inhibition of HDAC1 by fluorescent activity assay				Bioorg Med Chem Lett 21: 5735-8 (2011) Article DOI: 10.1016/j.bmcl.2011.08.022 BindingDB Entry DOI: 10.7270/Q2028RZ0
					More data for this Ligand-Target Pair