BDBM50354784 CHEMBL1834464

SMILES: Cc1ccc(cc1)-c1nnc(Nc2ncc(cn2)C(=O)NO)o1

InChI Key: InChIKey=AVIKWPWLKIRFIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50354784 (CHEMBL1834464) Show SMILES Cc1ccc(cc1)-c1nnc(Nc2ncc(cn2)C(=O)NO)o1 Show InChI InChI=1S/C14H12N6O3/c1-8-2-4-9(5-3-8)12-18-19-14(23-12)17-13-15-6-10(7-16-13)11(21)20-22/h2-7,22H,1H3,(H,20,21)(H,15,16,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas University Curated by ChEMBL					Assay Description Inhibition of HDAC1 by fluorescent activity assay				Bioorg Med Chem Lett 21: 5735-8 (2011) Article DOI: 10.1016/j.bmcl.2011.08.022 BindingDB Entry DOI: 10.7270/Q2028RZ0
					More data for this Ligand-Target Pair