BDBM50354836 CHEMBL1834491
SMILES: COc1cccc(Cn2ccc3cc(ccc23)-c2ccccc2)c1Oc1ccc(cc1C(O)=O)[N+]([O-])=O
InChI Key: InChIKey=YXJGFXIXETXYFV-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasminogen activator inhibitor-1 (Homo sapiens (Human)) | BDBM50354836 (CHEMBL1834491) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Zydus Research Centre Curated by ChEMBL | Assay Description Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assay | Bioorg Med Chem Lett 21: 5701-6 (2011) Article DOI: 10.1016/j.bmcl.2011.08.031 BindingDB Entry DOI: 10.7270/Q2B858JV | |||||||||||
More data for this Ligand-Target Pair |