BDBM50354919 CHEMBL1836893

SMILES: Nc1nc(cc2n(Cc3ccc(NCCN4CCCCC4)nc3)c(=O)[nH]c12)C(F)(F)F

InChI Key: InChIKey=QKUWZNZVQLRNKN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50354919 (CHEMBL1836893) Show SMILES Nc1nc(cc2n(Cc3ccc(NCCN4CCCCC4)nc3)c(=O)[nH]c12)C(F)(F)F Show InChI InChI=1S/C20H24F3N7O/c21-20(22,23)15-10-14-17(18(24)27-15)28-19(31)30(14)12-13-4-5-16(26-11-13)25-6-9-29-7-2-1-3-8-29/h4-5,10-11H,1-3,6-9,12H2,(H2,24,27)(H,25,26)(H,28,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at TLR7				Bioorg Med Chem Lett 21: 5939-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.076 BindingDB Entry DOI: 10.7270/Q2PK0GJN
					More data for this Ligand-Target Pair