BDBM50354930 CHEMBL1836884

SMILES: Nc1nc(cc2n(Cc3ccc(OCCN4CCCC4)nc3)c(=O)[nH]c12)C(F)(F)F

InChI Key: InChIKey=UBAJSVZYTYHQSD-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50354930 (CHEMBL1836884) Show SMILES Nc1nc(cc2n(Cc3ccc(OCCN4CCCC4)nc3)c(=O)[nH]c12)C(F)(F)F Show InChI InChI=1S/C19H21F3N6O2/c20-19(21,22)14-9-13-16(17(23)25-14)26-18(29)28(13)11-12-3-4-15(24-10-12)30-8-7-27-5-1-2-6-27/h3-4,9-10H,1-2,5-8,11H2,(H2,23,25)(H,26,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.90	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at TLR7 in human PBMC assessed as induction of type 1 interferon production				Bioorg Med Chem Lett 21: 5939-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.076 BindingDB Entry DOI: 10.7270/Q2PK0GJN
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50354930 (CHEMBL1836884) Show SMILES Nc1nc(cc2n(Cc3ccc(OCCN4CCCC4)nc3)c(=O)[nH]c12)C(F)(F)F Show InChI InChI=1S/C19H21F3N6O2/c20-19(21,22)14-9-13-16(17(23)25-14)26-18(29)28(13)11-12-3-4-15(24-10-12)30-8-7-27-5-1-2-6-27/h3-4,9-10H,1-2,5-8,11H2,(H2,23,25)(H,26,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.90	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at TLR7				Bioorg Med Chem Lett 21: 5939-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.076 BindingDB Entry DOI: 10.7270/Q2PK0GJN
					More data for this Ligand-Target Pair