BDBM50354944 CHEMBL1837066

SMILES: COCCN1CCN(CC1)c1ncccc1Cn1c2cc(nc(N)c2[nH]c1=O)C(F)(F)F

InChI Key: InChIKey=COTHODXDMUACTH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50354944 (CHEMBL1837066) Show SMILES COCCN1CCN(CC1)c1ncccc1Cn1c2cc(nc(N)c2[nH]c1=O)C(F)(F)F Show InChI InChI=1S/C20H24F3N7O2/c1-32-10-9-28-5-7-29(8-6-28)18-13(3-2-4-25-18)12-30-14-11-15(20(21,22)23)26-17(24)16(14)27-19(30)31/h2-4,11H,5-10,12H2,1H3,(H2,24,26)(H,27,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at TLR7 in human PBMC assessed as induction of type 1 interferon production				Bioorg Med Chem Lett 21: 5939-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.076 BindingDB Entry DOI: 10.7270/Q2PK0GJN
					More data for this Ligand-Target Pair