BDBM50354966 CHEMBL1836931

SMILES: COc1ccc(c(C)c1)-n1cnc2c(NC(C3CC3)C3CC3)nc(C)nc12

InChI Key: InChIKey=RCQLVHRIOXVLQM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50354966 (CHEMBL1836931) Show SMILES COc1ccc(c(C)c1)-n1cnc2c(NC(C3CC3)C3CC3)nc(C)nc12 Show InChI InChI=1S/C21H25N5O/c1-12-10-16(27-3)8-9-17(12)26-11-22-19-20(23-13(2)24-21(19)26)25-18(14-4-5-14)15-6-7-15/h8-11,14-15,18H,4-7H2,1-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at recombinant human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP formation				Bioorg Med Chem Lett 21: 6108-11 (2011) Article DOI: 10.1016/j.bmcl.2011.08.040 BindingDB Entry DOI: 10.7270/Q2F19046
					More data for this Ligand-Target Pair