BDBM50354970 CHEMBL1836935

SMILES: COc1ccc(cc1)-n1c(CC2CC2)nc2c(NC(C3CC3)C3CC3)nc(C)nc12

InChI Key: InChIKey=UZZOZZVNYNABCT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50354970 (CHEMBL1836935) Show SMILES COc1ccc(cc1)-n1c(CC2CC2)nc2c(NC(C3CC3)C3CC3)nc(C)nc12 Show InChI InChI=1S/C24H29N5O/c1-14-25-23(28-21(16-5-6-16)17-7-8-17)22-24(26-14)29(20(27-22)13-15-3-4-15)18-9-11-19(30-2)12-10-18/h9-12,15-17,21H,3-8,13H2,1-2H3,(H,25,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	308	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at recombinant human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP formation				Bioorg Med Chem Lett 21: 6108-11 (2011) Article DOI: 10.1016/j.bmcl.2011.08.040 BindingDB Entry DOI: 10.7270/Q2F19046
					More data for this Ligand-Target Pair