BDBM50354978 CHEMBL1836942

SMILES: CCOc1ccc(cc1)-n1c(C)nc2c(NC(C3CC3)C3CC3)nc(C)nc12

InChI Key: InChIKey=UEXNITFRYZVFAP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50354978 (CHEMBL1836942) Show SMILES CCOc1ccc(cc1)-n1c(C)nc2c(NC(C3CC3)C3CC3)nc(C)nc12 Show InChI InChI=1S/C22H27N5O/c1-4-28-18-11-9-17(10-12-18)27-14(3)25-20-21(23-13(2)24-22(20)27)26-19(15-5-6-15)16-7-8-16/h9-12,15-16,19H,4-8H2,1-3H3,(H,23,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at recombinant human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP formation				Bioorg Med Chem Lett 21: 6108-11 (2011) Article DOI: 10.1016/j.bmcl.2011.08.040 BindingDB Entry DOI: 10.7270/Q2F19046
					More data for this Ligand-Target Pair