BDBM50355076 CHEMBL1835753

SMILES: O=C(Cc1ccc(cc1)C(=O)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12)c1ccccc1

InChI Key: InChIKey=DTBLEIJDLCGKOO-GDLZYMKVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50355076 (CHEMBL1835753) Show SMILES O=C(Cc1ccc(cc1)C(=O)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12)c1ccccc1 |r| Show InChI InChI=1S/C31H34N2O2/c34-30(25-8-3-1-4-9-25)21-23-12-15-26(16-13-23)31(35)32-29-11-7-10-27-20-24(14-17-28(27)29)22-33-18-5-2-6-19-33/h1,3-4,8-9,12-17,20,29H,2,5-7,10-11,18-19,21-22H2,(H,32,35)/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human B1 receptor				J Med Chem 54: 7232-46 (2011) Article DOI: 10.1021/jm200808v BindingDB Entry DOI: 10.7270/Q28C9WP1
					More data for this Ligand-Target Pair