BDBM50355477 CHEMBL1835738

SMILES: COc1ccc(Nc2nc(N)n(n2)-c2ccccc2Cl)cc1OC

InChI Key: InChIKey=RXCGURKRNJNTEK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50355477 (CHEMBL1835738) Show SMILES COc1ccc(Nc2nc(N)n(n2)-c2ccccc2Cl)cc1OC Show InChI InChI=1S/C16H16ClN5O2/c1-23-13-8-7-10(9-14(13)24-2)19-16-20-15(18)22(21-16)12-6-4-3-5-11(12)17/h3-9H,1-2H3,(H3,18,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation counting				J Med Chem 54: 7184-92 (2011) Article DOI: 10.1021/jm200712h BindingDB Entry DOI: 10.7270/Q2DZ08QQ
					More data for this Ligand-Target Pair