BDBM50355483 CHEMBL1835750

SMILES: Nc1nc(Nc2ccc(cc2)C(O)CCCN2CCOCC2)nn1-c1ccccn1

InChI Key: InChIKey=JNROOHWIIJBSJF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50355483 (CHEMBL1835750) Show SMILES Nc1nc(Nc2ccc(cc2)C(O)CCCN2CCOCC2)nn1-c1ccccn1 Show InChI InChI=1S/C21H27N7O2/c22-20-25-21(26-28(20)19-5-1-2-10-23-19)24-17-8-6-16(7-9-17)18(29)4-3-11-27-12-14-30-15-13-27/h1-2,5-10,18,29H,3-4,11-15H2,(H3,22,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation counting				J Med Chem 54: 7184-92 (2011) Article DOI: 10.1021/jm200712h BindingDB Entry DOI: 10.7270/Q2DZ08QQ
					More data for this Ligand-Target Pair