BDBM50355574 CHEMBL1910748

SMILES: Cc1sc2nc(c(\C=N\NC(N)=N)n2c1C)-c1ccc(Cl)c(c1)[N+]([O-])=O

InChI Key: InChIKey=CWVQXDDCNNKJMV-KPSZGOFPSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50355574 (CHEMBL1910748) Show SMILES Cc1sc2nc(c(\C=N\NC(N)=N)n2c1C)-c1ccc(Cl)c(c1)[N+]([O-])=O Show InChI InChI=1S/C15H14ClN7O2S/c1-7-8(2)26-15-20-13(12(22(7)15)6-19-21-14(17)18)9-3-4-10(16)11(5-9)23(24)25/h3-6H,1-2H3,(H4,17,18,21)/b19-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK1 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50355574 (CHEMBL1910748) Show SMILES Cc1sc2nc(c(\C=N\NC(N)=N)n2c1C)-c1ccc(Cl)c(c1)[N+]([O-])=O Show InChI InChI=1S/C15H14ClN7O2S/c1-7-8(2)26-15-20-13(12(22(7)15)6-19-21-14(17)18)9-3-4-10(16)11(5-9)23(24)25/h3-6H,1-2H3,(H4,17,18,21)/b19-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50355574 (CHEMBL1910748) Show SMILES Cc1sc2nc(c(\C=N\NC(N)=N)n2c1C)-c1ccc(Cl)c(c1)[N+]([O-])=O Show InChI InChI=1S/C15H14ClN7O2S/c1-7-8(2)26-15-20-13(12(22(7)15)6-19-21-14(17)18)9-3-4-10(16)11(5-9)23(24)25/h3-6H,1-2H3,(H4,17,18,21)/b19-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair