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BDBM50355632 CHEMBL1910866

SMILES: CC(C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)N1CC(C1)Oc1cc(O)ccc1F

InChI Key: InChIKey=FYLDYFDWQWVALO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355632   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50355632
PNG
(CHEMBL1910866)
Show SMILES CC(C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)N1CC(C1)Oc1cc(O)ccc1F
Show InChI InChI=1S/C28H31FN2O3/c1-27(2,31-18-23(19-31)34-25-17-22(32)13-14-24(25)29)15-16-28(26(30)33,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-14,17,23,32H,15-16,18-19H2,1-2H3,(H2,30,33)
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PC cid
PC sid
UniChem

Patents

Article
PubMed
0.710n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant M3 receptor expressed in CHO-K1 cells assessed as inhibition of carbamoyl choline-induced calcium currents a...


J Med Chem 54: 6888-904 (2011)


Article DOI: 10.1021/jm200884j
BindingDB Entry DOI: 10.7270/Q2CZ37JW
More data for this
Ligand-Target Pair