BDBM50356336 CHEMBL1911413

SMILES: OC(=O)CC1(Cc2ccccc2Cl)C2CC3CC(C2)CC1C3

InChI Key: InChIKey=KPTQADNKXRYGNW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50356336 (CHEMBL1911413) Show SMILES OC(=O)CC1(Cc2ccccc2Cl)C2CC3CC(C2)CC1C3 |TLB:21:20:18:14.15.16,3:4:14.21.15:19.17.18,THB:21:15:4.20.19:18,16:15:4:19.17.18,16:17:4:14.21.15,3:4:18:14.15.16,5:4:14.21.15:19.17.18,(-6.8,-7.84,;-5.47,-8.62,;-4.13,-7.85,;-5.47,-10.16,;-4.13,-10.94,;-4.87,-12.29,;-6.41,-12.32,;-7.2,-10.99,;-8.74,-11.02,;-9.48,-12.37,;-8.68,-13.69,;-7.15,-13.66,;-6.35,-14.97,;-2.93,-9.66,;-1.6,-10.15,;-.21,-9.8,;-.2,-8.27,;-1.59,-7.69,;-2.94,-8.17,;-2.63,-8.93,;-2.63,-10.52,;-1.22,-11.08,)| Show InChI InChI=1S/C19H23ClO2/c20-17-4-2-1-3-14(17)10-19(11-18(21)22)15-6-12-5-13(8-15)9-16(19)7-12/h1-4,12-13,15-16H,5-11H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD-1				Bioorg Med Chem Lett 21: 6699-704 (2011) Article DOI: 10.1016/j.bmcl.2011.09.055 BindingDB Entry DOI: 10.7270/Q2Q240NV
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50356336 (CHEMBL1911413) Show SMILES OC(=O)CC1(Cc2ccccc2Cl)C2CC3CC(C2)CC1C3 |TLB:21:20:18:14.15.16,3:4:14.21.15:19.17.18,THB:21:15:4.20.19:18,16:15:4:19.17.18,16:17:4:14.21.15,3:4:18:14.15.16,5:4:14.21.15:19.17.18,(-6.8,-7.84,;-5.47,-8.62,;-4.13,-7.85,;-5.47,-10.16,;-4.13,-10.94,;-4.87,-12.29,;-6.41,-12.32,;-7.2,-10.99,;-8.74,-11.02,;-9.48,-12.37,;-8.68,-13.69,;-7.15,-13.66,;-6.35,-14.97,;-2.93,-9.66,;-1.6,-10.15,;-.21,-9.8,;-.2,-8.27,;-1.59,-7.69,;-2.94,-8.17,;-2.63,-8.93,;-2.63,-10.52,;-1.22,-11.08,)| Show InChI InChI=1S/C19H23ClO2/c20-17-4-2-1-3-14(17)10-19(11-18(21)22)15-6-12-5-13(8-15)9-16(19)7-12/h1-4,12-13,15-16H,5-11H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD-1				Bioorg Med Chem Lett 21: 6699-704 (2011) Article DOI: 10.1016/j.bmcl.2011.09.055 BindingDB Entry DOI: 10.7270/Q2Q240NV
					More data for this Ligand-Target Pair