BDBM50356341 CHEMBL1911408

SMILES: OC(=O)CC1(C2CC3CC(C2)CC1C3)c1ccc(Cl)cc1

InChI Key: InChIKey=LZKWXNMCVNQXEH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50356341 (CHEMBL1911408) Show SMILES OC(=O)CC1(C2CC3CC(C2)CC1C3)c1ccc(Cl)cc1 |TLB:13:12:10:6.7.8,3:4:6.13.7:11.9.10,THB:13:7:4.12.11:10,8:7:4:11.9.10,8:9:4:6.13.7,3:4:10:6.7.8,14:4:6.13.7:11.9.10,(6.49,-37.27,;7.83,-38.04,;9.16,-37.27,;7.82,-39.58,;9.17,-40.36,;10.36,-39.08,;11.69,-39.57,;13.09,-39.23,;13.1,-37.7,;11.7,-37.12,;10.36,-37.6,;10.66,-38.35,;10.67,-39.94,;12.08,-40.51,;8.42,-41.71,;6.88,-41.74,;6.14,-43.09,;6.94,-44.41,;6.2,-45.76,;8.49,-44.37,;9.23,-43.02,)| Show InChI InChI=1S/C18H21ClO2/c19-16-3-1-13(2-4-16)18(10-17(20)21)14-6-11-5-12(8-14)9-15(18)7-11/h1-4,11-12,14-15H,5-10H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD-1				Bioorg Med Chem Lett 21: 6699-704 (2011) Article DOI: 10.1016/j.bmcl.2011.09.055 BindingDB Entry DOI: 10.7270/Q2Q240NV
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50356341 (CHEMBL1911408) Show SMILES OC(=O)CC1(C2CC3CC(C2)CC1C3)c1ccc(Cl)cc1 |TLB:13:12:10:6.7.8,3:4:6.13.7:11.9.10,THB:13:7:4.12.11:10,8:7:4:11.9.10,8:9:4:6.13.7,3:4:10:6.7.8,14:4:6.13.7:11.9.10,(6.49,-37.27,;7.83,-38.04,;9.16,-37.27,;7.82,-39.58,;9.17,-40.36,;10.36,-39.08,;11.69,-39.57,;13.09,-39.23,;13.1,-37.7,;11.7,-37.12,;10.36,-37.6,;10.66,-38.35,;10.67,-39.94,;12.08,-40.51,;8.42,-41.71,;6.88,-41.74,;6.14,-43.09,;6.94,-44.41,;6.2,-45.76,;8.49,-44.37,;9.23,-43.02,)| Show InChI InChI=1S/C18H21ClO2/c19-16-3-1-13(2-4-16)18(10-17(20)21)14-6-11-5-12(8-14)9-15(18)7-11/h1-4,11-12,14-15H,5-10H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD-1				Bioorg Med Chem Lett 21: 6699-704 (2011) Article DOI: 10.1016/j.bmcl.2011.09.055 BindingDB Entry DOI: 10.7270/Q2Q240NV
					More data for this Ligand-Target Pair