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SMILES: Nc1scc2c1c(NCCO)nc1ncnc(N)c21

InChI Key: InChIKey=FZZWYTXTWFAEGS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50356618 (CHEMBL1910272) Show SMILES Nc1scc2c1c(NCCO)nc1ncnc(N)c21 Show InChI InChI=1S/C11H12N6OS/c12-8-6-5-3-19-9(13)7(5)11(14-1-2-18)17-10(6)16-4-15-8/h3-4,18H,1-2,13H2,(H3,12,14,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Organization for Drug Control& Research Curated by ChEMBL					Assay Description Inhibition of human EGFR				Eur J Med Chem 46: 5825-32 (2011) Article DOI: 10.1016/j.ejmech.2011.09.041 BindingDB Entry DOI: 10.7270/Q21C1X8V
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50356618 (CHEMBL1910272) Show SMILES Nc1scc2c1c(NCCO)nc1ncnc(N)c21 Show InChI InChI=1S/C11H12N6OS/c12-8-6-5-3-19-9(13)7(5)11(14-1-2-18)17-10(6)16-4-15-8/h3-4,18H,1-2,13H2,(H3,12,14,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
National Organization for Drug Control& Research Curated by ChEMBL					Assay Description Inhibition of CDK2/cyclin A expressed in baculovirus infected insect Sf21 cells using [gamma-P32]ATP and histone H1 as substrate after 10 mins by rad...				Eur J Med Chem 46: 5825-32 (2011) Article DOI: 10.1016/j.ejmech.2011.09.041 BindingDB Entry DOI: 10.7270/Q21C1X8V
					More data for this Ligand-Target Pair