BDBM50356628 CHEMBL1914697
SMILES: CN1C2CCC1[C@@H](CNc1ccc(Br)nc1)[C@H](C2)c1ccc(Cl)cc1
InChI Key: InChIKey=CSQWTWVZSNGFRN-IAFLDTSXSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50356628 (CHEMBL1914697) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Radiopharmaceuticals (Beijing Normal University) Curated by ChEMBL | Assay Description Displacement of [125I]-IDAM from SERT transfected in pig LLC-PK1 cells by radioligand competition binding assay | Bioorg Med Chem Lett 21: 2962-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.051 BindingDB Entry DOI: 10.7270/Q2WM1DT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50356628 (CHEMBL1914697) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Radiopharmaceuticals (Beijing Normal University) Curated by ChEMBL | Assay Description Displacement of [125I]-IPT from DAT transfected in pig LLC-PK1 cells by radioligand competition binding assay | Bioorg Med Chem Lett 21: 2962-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.051 BindingDB Entry DOI: 10.7270/Q2WM1DT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50356628 (CHEMBL1914697) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Radiopharmaceuticals (Beijing Normal University) Curated by ChEMBL | Assay Description Displacement of [125I]-INXT from NET transfected in pig LLC-PK1 cells by radioligand competition binding assay | Bioorg Med Chem Lett 21: 2962-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.051 BindingDB Entry DOI: 10.7270/Q2WM1DT0 | |||||||||||
More data for this Ligand-Target Pair |