BDBM50356640 CHEMBL1914706

SMILES: CC(C)(C)OC(=O)Nc1ccc(Cn2cc(NC(=O)CCCCCCC(=O)NO)cn2)cc1

InChI Key: InChIKey=RNBIJFLCSVSISV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50356640 (CHEMBL1914706) Show SMILES CC(C)(C)OC(=O)Nc1ccc(Cn2cc(NC(=O)CCCCCCC(=O)NO)cn2)cc1 Show InChI InChI=1S/C23H33N5O5/c1-23(2,3)33-22(31)26-18-12-10-17(11-13-18)15-28-16-19(14-24-28)25-20(29)8-6-4-5-7-9-21(30)27-32/h10-14,16,32H,4-9,15H2,1-3H3,(H,25,29)(H,26,31)(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 using Fluor de Lys as substrate				J Med Chem 54: 4350-64 (2011) Article DOI: 10.1021/jm2001025 BindingDB Entry DOI: 10.7270/Q2RX9CG0
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50356640 (CHEMBL1914706) Show SMILES CC(C)(C)OC(=O)Nc1ccc(Cn2cc(NC(=O)CCCCCCC(=O)NO)cn2)cc1 Show InChI InChI=1S/C23H33N5O5/c1-23(2,3)33-22(31)26-18-12-10-17(11-13-18)15-28-16-19(14-24-28)25-20(29)8-6-4-5-7-9-21(30)27-32/h10-14,16,32H,4-9,15H2,1-3H3,(H,25,29)(H,26,31)(H,27,30)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3/NCoR2 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC				J Med Chem 54: 4350-64 (2011) Article DOI: 10.1021/jm2001025 BindingDB Entry DOI: 10.7270/Q2RX9CG0
					More data for this Ligand-Target Pair