BDBM50356949 CHEMBL1916057

SMILES: ON1CC=CC[C@@H](NS(=O)(=O)c2ccc(Oc3ccccc3)cc2)C1=O

InChI Key: InChIKey=QHXQILHKQUVTBK-QGZVFWFLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356949   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50356949 (CHEMBL1916057) Show SMILES ON1CC=CC[C@@H](NS(=O)(=O)c2ccc(Oc3ccccc3)cc2)C1=O |r,c:3| Show InChI InChI=1S/C18H18N2O5S/c21-18-17(8-4-5-13-20(18)22)19-26(23,24)16-11-9-15(10-12-16)25-14-6-2-1-3-7-14/h1-7,9-12,17,19,22H,8,13H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of full length human MMP2 (amino acids 1 to 660) using acetyl-Cys(Eu)-Pro-Leu-Gly-Leu-Lys-(QSY7)-Ala-Arg-amide as substrate preincubated f...				Bioorg Med Chem Lett 21: 6485-90 (2011) Article DOI: 10.1016/j.bmcl.2011.08.068 BindingDB Entry DOI: 10.7270/Q2BP0353
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50356949 (CHEMBL1916057) Show SMILES ON1CC=CC[C@@H](NS(=O)(=O)c2ccc(Oc3ccccc3)cc2)C1=O |r,c:3| Show InChI InChI=1S/C18H18N2O5S/c21-18-17(8-4-5-13-20(18)22)19-26(23,24)16-11-9-15(10-12-16)25-14-6-2-1-3-7-14/h1-7,9-12,17,19,22H,8,13H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human MMP9 catalytic domain (amino acids 107 to 446) using acetyl-Cys(Eu)-Pro-Leu-Gly-Leu-Lys-(QSY7)-Ala-Arg-amide as substrate preincu...				Bioorg Med Chem Lett 21: 6485-90 (2011) Article DOI: 10.1016/j.bmcl.2011.08.068 BindingDB Entry DOI: 10.7270/Q2BP0353
					More data for this Ligand-Target Pair