BDBM50357148 CHEMBL1917462
SMILES: Cc1c(Sc2ccc(Cl)cc2)c2c(Cl)nccc2n1CC(O)=O
InChI Key: InChIKey=XEYDGQLGRXJVCH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50357148 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
G protein-coupled receptor 44
(Homo sapiens (Human)) | BDBM50357148
(CHEMBL1917462)Show InChI InChI=1S/C16H12Cl2N2O2S/c1-9-15(23-11-4-2-10(17)3-5-11)14-12(6-7-19-16(14)18)20(9)8-13(21)22/h2-7H,8H2,1H3,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oxagen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of CRTH2 |
J Med Chem 55: 2915-31 (2012)
Article DOI: 10.1021/jm2013997 BindingDB Entry DOI: 10.7270/Q2Z0398R |
More data for this Ligand-Target Pair | |
G protein-coupled receptor 44
(Homo sapiens (Human)) | BDBM50357148
(CHEMBL1917462)Show InChI InChI=1S/C16H12Cl2N2O2S/c1-9-15(23-11-4-2-10(17)3-5-11)14-12(6-7-19-16(14)18)20(9)8-13(21)22/h2-7H,8H2,1H3,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood
Curated by ChEMBL
| Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor |
Bioorg Med Chem Lett 21: 6288-92 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225 |
More data for this Ligand-Target Pair | |