BDBM50357251 CHEMBL1916474

SMILES: CCOCCn1c2cc(nnc2c(nc1=O)N1CCN(CCO)CC1)-c1ccc(OC)nc1

InChI Key: InChIKey=SHUANNVAXQZEAM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50357251 (CHEMBL1916474) Show SMILES CCOCCn1c2cc(nnc2c(nc1=O)N1CCN(CCO)CC1)-c1ccc(OC)nc1 Show InChI InChI=1S/C22H29N7O4/c1-3-33-13-11-29-18-14-17(16-4-5-19(32-2)23-15-16)25-26-20(18)21(24-22(29)31)28-8-6-27(7-9-28)10-12-30/h4-5,14-15,30H,3,6-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 21: 6348-52 (2011) Article DOI: 10.1016/j.bmcl.2011.08.106 BindingDB Entry DOI: 10.7270/Q2J67HB0
					More data for this Ligand-Target Pair