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BDBM50357279 CHEMBL1916504

SMILES: CN1CC2CN(CC2C1)c1nc(C)ccc1C#N

InChI Key: InChIKey=CHIPXHGRWDCHHS-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357279   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))		BDBM50357279
PNG
(CHEMBL1916504)
Show SMILES CN1CC2CN(CC2C1)c1nc(C)ccc1C#N
Show InChI InChI=1S/C14H18N4/c1-10-3-4-11(5-15)14(16-10)18-8-12-6-17(2)7-13(12)9-18/h3-4,12-13H,6-9H2,1-2H3
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PubMed
 930n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting technique

Bioorg Med Chem Lett 21: 6591-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.114
BindingDB Entry DOI: 10.7270/Q2DF6RNQ
More data for this
Ligand-Target Pair