BindingDB PrimarySearch

BDBM50357290 CHEMBL1916697

SMILES: COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F

InChI Key: InChIKey=WGXIPXHUOIQNGL-UHFFFAOYSA-N

Data: 8 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50357290
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50357290 (CHEMBL1916697) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ...				Bioorg Med Chem Lett 21: 6608-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.024 BindingDB Entry DOI: 10.7270/Q2513ZM9
Amira Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50357290 (CHEMBL1916697) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting				Bioorg Med Chem Lett 21: 6608-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.024 BindingDB Entry DOI: 10.7270/Q2513ZM9
Amira Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50357290 (CHEMBL1916697) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma...				Bioorg Med Chem Lett 21: 6608-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.024 BindingDB Entry DOI: 10.7270/Q2513ZM9
Amira Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50357290 (CHEMBL1916697) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]-SQ-29,548 from human TP receptor expressed in human platelet membranes				Bioorg Med Chem Lett 21: 6608-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.024 BindingDB Entry DOI: 10.7270/Q2513ZM9
Amira Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50357290 (CHEMBL1916697) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human CYP2C9				Bioorg Med Chem Lett 21: 6608-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.024 BindingDB Entry DOI: 10.7270/Q2513ZM9
Amira Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50357290 (CHEMBL1916697) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human CYP2D6				Bioorg Med Chem Lett 21: 6608-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.024 BindingDB Entry DOI: 10.7270/Q2513ZM9
Amira Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50357290 (CHEMBL1916697) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from human DP1 receptor expressed in human platelet membranes				Bioorg Med Chem Lett 21: 6608-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.024 BindingDB Entry DOI: 10.7270/Q2513ZM9
Amira Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50357290 (CHEMBL1916697) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human CYP3A4				Bioorg Med Chem Lett 21: 6608-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.024 BindingDB Entry DOI: 10.7270/Q2513ZM9
Amira Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair