BDBM50357555 CHEMBL1915172

SMILES: COC(=O)[C@H]1Cc2c(CN1C(=O)NCCc1ccccc1)[nH]c1ccccc21

InChI Key: InChIKey=NUCOWQPFXTVMOO-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50357555 (CHEMBL1915172) Show SMILES COC(=O)[C@H]1Cc2c(CN1C(=O)NCCc1ccccc1)[nH]c1ccccc21 |r| Show InChI InChI=1S/C22H23N3O3/c1-28-21(26)20-13-17-16-9-5-6-10-18(16)24-19(17)14-25(20)22(27)23-12-11-15-7-3-2-4-8-15/h2-10,20,24H,11-14H2,1H3,(H,23,27)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells pretreated 15 mins before LPS challenge measured after 20...				Bioorg Med Chem 19: 6182-95 (2011) Article DOI: 10.1016/j.bmc.2011.09.020 BindingDB Entry DOI: 10.7270/Q2Z89CTS
					More data for this Ligand-Target Pair