BDBM50357889 CHEMBL1916346

SMILES: [O-][n+]1ccc2c(ccnc2c1-c1ccccc1F)-c1ccc(F)cc1F

InChI Key: InChIKey=JPUMCKSXTCQYOX-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50357889 (CHEMBL1916346) Show SMILES [O-][n+]1ccc2c(ccnc2c1-c1ccccc1F)-c1ccc(F)cc1F |(14.31,-20.58,;15.64,-19.81,;15.65,-18.26,;16.98,-17.49,;18.31,-18.26,;19.64,-17.48,;20.98,-18.26,;20.98,-19.81,;19.64,-20.57,;18.31,-19.8,;16.98,-20.58,;16.98,-22.11,;18.31,-22.87,;18.32,-24.41,;16.99,-25.19,;15.65,-24.42,;15.65,-22.88,;14.31,-22.11,;19.64,-15.95,;18.31,-15.18,;18.31,-13.65,;19.65,-12.87,;19.65,-11.33,;20.98,-13.64,;20.98,-15.18,;22.31,-15.95,)| Show InChI InChI=1S/C20H11F3N2O/c21-12-5-6-14(18(23)11-12)13-7-9-24-19-15(13)8-10-25(26)20(19)16-3-1-2-4-17(16)22/h1-11H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	333	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human p38alpha MAP kinase after 1 hr by FRET analysis				J Med Chem 54: 7899-910 (2011) Article DOI: 10.1021/jm200975u BindingDB Entry DOI: 10.7270/Q2MW2HKR
					More data for this Ligand-Target Pair