BDBM50358060 CHEMBL1914666

SMILES: CC(Nc1ncnc2[nH]c(cc12)-c1ccc(O)cc1)c1cccc2ccccc12

InChI Key: InChIKey=XXNUFRHVPZASID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50358060 (CHEMBL1914666) Show SMILES CC(Nc1ncnc2[nH]c(cc12)-c1ccc(O)cc1)c1cccc2ccccc12 Show InChI InChI=1S/C24H20N4O/c1-15(19-8-4-6-16-5-2-3-7-20(16)19)27-23-21-13-22(28-24(21)26-14-25-23)17-9-11-18(29)12-10-17/h2-15,29H,1H3,(H2,25,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Norwegian University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of EGFR by Z-LYTE assay				Eur J Med Chem 46: 6002-14 (2011) Article DOI: 10.1016/j.ejmech.2011.10.012 BindingDB Entry DOI: 10.7270/Q26M377V
					More data for this Ligand-Target Pair