BDBM50358442 CHEMBL1922998

SMILES: FC(F)(F)Oc1cccc(Oc2ccc(Nc3ncnc4cc[nH]c34)cc2Cl)c1

InChI Key: InChIKey=PEGQWGLLBPWDAS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50358442 (CHEMBL1922998) Show SMILES FC(F)(F)Oc1cccc(Oc2ccc(Nc3ncnc4cc[nH]c34)cc2Cl)c1 Show InChI InChI=1S/C19H12ClF3N4O2/c20-14-8-11(27-18-17-15(6-7-24-17)25-10-26-18)4-5-16(14)28-12-2-1-3-13(9-12)29-19(21,22)23/h1-10,24H,(H,25,26,27)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human N-terminus peptide (DYKDDDD)-tagged HER2 expressed in baculovirus infected insect cells using [gamma-32P]ATP as substrate after 6...				J Med Chem 54: 8030-50 (2011) Article DOI: 10.1021/jm2008634 BindingDB Entry DOI: 10.7270/Q23R0T93
					More data for this Ligand-Target Pair